Author: Luis M. Colon-Perez; Kristen R. Ibanez; Mallory Suarez; Kristin Torroella; Kelly Acuna; Edward Ofori; Yona Levites; David E. Vaillancourt; Todd E. Golde; Paramita Chakrabarty; Marcelo Febo
Title: Increased Neurite Orientation-Dispersion and Density in the TgCRND8 Mouse Model of Amyloidosis: Inverse Relation with Functional Connectome Clustering and Modulation by Interleukin-6 Document date: 2019_2_27
ID: hyeygk64_12
Snippet: The following experimental groups were included in this study: nTg-Controls expressing AAV-EGFP (n = 14), nTg-IL6 expressing IL6 (n = 14), TgCRND8-Controls expressing AAV-EGFP (n = 10) and TgCRND8-IL6 expressing IL6 (n = 10). All 4 groups were sex-balanced. Statistical analysis showed no sex differences, thus data for male and female mice were grouped. One dMRI scan in the nTg-IL6 group had excess, uncorrectable noise and was removed (leaving 13 .....
Document: The following experimental groups were included in this study: nTg-Controls expressing AAV-EGFP (n = 14), nTg-IL6 expressing IL6 (n = 14), TgCRND8-Controls expressing AAV-EGFP (n = 10) and TgCRND8-IL6 expressing IL6 (n = 10). All 4 groups were sex-balanced. Statistical analysis showed no sex differences, thus data for male and female mice were grouped. One dMRI scan in the nTg-IL6 group had excess, uncorrectable noise and was removed (leaving 13 subjects in this group and a total of 47 mice for the entire study).
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