Author: Pei-Hui Wang; Yun Cheng
Title: Increasing Host Cellular Receptor—Angiotensin-Converting Enzyme 2 (ACE2) Expression by Coronavirus may Facilitate 2019-nCoV Infection Document date: 2020_2_27
ID: epy7774j_28
Snippet: . CC-BY-NC-ND 4.0 International license author/funder. It is made available under a The copyright holder for this preprint (which was not peer-reviewed) is the . https://doi.org/10.1101/2020.02.24.963348 doi: bioRxiv preprint immune cells and pulmonary epithelium are also the main sites of injury (Gu et al., 2005) . Acute kidney injury is a predictor of high mortality in SARS patients (Chu et al., 2005) . In the lung, human ACE2 is primarily exis.....
Document: . CC-BY-NC-ND 4.0 International license author/funder. It is made available under a The copyright holder for this preprint (which was not peer-reviewed) is the . https://doi.org/10.1101/2020.02.24.963348 doi: bioRxiv preprint immune cells and pulmonary epithelium are also the main sites of injury (Gu et al., 2005) . Acute kidney injury is a predictor of high mortality in SARS patients (Chu et al., 2005) . In the lung, human ACE2 is primarily existed in type II and type I alveolar epithelial cells. ACE2 is mainly expressed in AT2 cells and also detected in AT1 cells, airway epithelial cells, fibroblasts, endothelial cells, and macrophages (Wei et al.
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