Author: Lloyd A. C. Chapman; Simon E. F. Spencer; Timothy M. Pollington; Chris P. Jewell; Dinesh Mondal; Jorge Alvar; T. Deirdre Hollingsworth; Mary M. Cameron; Caryn Bern; Graham F. Medley
Title: Inferring transmission trees to guide targeting of interventions against visceral leishmaniasis and post-kala-azar dermal leishmaniasis Document date: 2020_2_25
ID: nqn1qzcu_6
Snippet: The times after onset of symptoms in the infector at which 336 secondary VL cases become infected are typically longer for 337 PKDL infectors than for VL infectors (Fig. 4B) detected after a longer delay than subsequent cases and there 356 will be some delay in mounting a reactive intervention, such 357 as active case detection and/or targeted IRS around the index 358 case(s), interventions will need to be applied in a large radius 359 (up to 500.....
Document: The times after onset of symptoms in the infector at which 336 secondary VL cases become infected are typically longer for 337 PKDL infectors than for VL infectors (Fig. 4B) detected after a longer delay than subsequent cases and there 356 will be some delay in mounting a reactive intervention, such 357 as active case detection and/or targeted IRS around the index 358 case(s), interventions will need to be applied in a large radius 359 (up to 500m) around index cases to be confident of capturing 360 all secondary cases and limiting transmission.
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