Selected article for: "model fit and recent strain"

Author: Bingyi Yang; Justin Lessler; Huachen Zhu; Chaoqiang Jiang; Jonathan M. Read; James A Hay; Kin On Kwok; Ruiyin Shen; Yi Guan; Steven Riley; Derek A.T. Cummings
Title: Life course exposures continually shape antibody profile and risk of seroconversion to influenza
  • Document date: 2020_1_16
  • ID: cyxn7dpw_18
    Snippet: (i.e. nAUC, nW 10 , nW 40 , and nATY) of strains up to and including the i-2th strain ("immunity of non-recent strains" hereafter). We found including nAUC or nW40 improved model fit (Table 1, figs. S6 and 7). After adjustment for pre-existing titer to strain i, we found pre-existing nAUC and nW 40 were each positively associated with seroconversion (Table 1 and tables S3, S5 to S7) . Taking A/Texas/2012 as an example, pre-existing titer to A/Tex.....
    Document: (i.e. nAUC, nW 10 , nW 40 , and nATY) of strains up to and including the i-2th strain ("immunity of non-recent strains" hereafter). We found including nAUC or nW40 improved model fit (Table 1, figs. S6 and 7). After adjustment for pre-existing titer to strain i, we found pre-existing nAUC and nW 40 were each positively associated with seroconversion (Table 1 and tables S3, S5 to S7) . Taking A/Texas/2012 as an example, pre-existing titer to A/Texas/2012 was negatively associated with the risk of seroconversion (OR: 0.45; 95% CI, 0.35 to 0.57; Model 3 in Table 1) , while there was an increased risk of seroconversion associated with higher pre-existing nAUC (OR: 1.21; 95% CI, 1.10 to 1.34) and nW40 (OR: 5.53; 95% CI, 2.15 to 14.57) .

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