Mechanical Ventilator Milano (MVM):A Novel Mechanical Ventilator Designed for Mass Scale Production in response to the COVID-19 Pandemics

Galbiati Cristiano; Walter Bonivento; Mauro Caravati; Marco Razeti; Sandro DeCecco; Giuliana Fiorillo; Federico Gabriele; Roberto Tartaglia; Alessandro Razeto; Davide Sablone; Eugenio Scapparone; Gemma Testera; Marco Rescigno; Davide Franco; Iza Kochanek; Cary Kendziora; Stephen H. Pordes; Hanguo Wang; Andrea Ianni; Art McDonald; L. Molinari Tosatti; T. Dinon; M. Malosio; D. Minuzzo; A. Zardoni; A. Prini

The copyright holder for this preprint (which was not peer-reviewed) is the . doctors and nurses a direct visual monitoring of the inspiratory pressure and of the expiratory flow; Small Number of Components: the MVM consist of a medical care flowmeter [14] in use for direct regulation of the maximum flow rate, a oxygen-therapy humidifier [14] , a non-vented non invasive ventilation (NIV) mask [15] , two electrically-controlled, VDCactuated pneumatic valves, a pressure sensor, a control system directly connected to the pneumatic valves and to the control sensor, and a backup VDC battery connected to the control system; Ease of Procurement: the parts required for the construction of the MVM have been selected by investigating current inventories available worldwide at major resellers of hardware suppliers. The parts selected are also characterized by their ease of mass-scale manufacturing; Ease of Construction: assembly of the parts into a complete MVM can be completed with a set of limited and clear instructions. The process for loading the software into the controller is simple. The controller software is open source and available for customizations by end users; Cost Containment: the total cost of components is a few hundreds of e 's. Ease of Deployment: the only required facilities are a line of pressurized oxygen and standard AC electric power (either 220 V or 110 V). The MVM can be deployed wherever a source of pressurized oxygen can be made available. It is suitable for home care and for use in ambulances. It is convenient to deploy in care clinics with centralized oxygen supply systems, such as COVID hospitals or COVID-care areas in general hospitals; Customizability: the MVM can operate in different configurations (independent and patient assisted) as described in Section 3. The operating parameters can be tuned by the operator with a simple user interface; Scalability: the MVM control system is based an a WiFi micro-controller which allows to monitor and tune the parameters of multiple units with a single work station; Reliability: all the components in this units are commercial and readily available. The reliability of MVM has to be carefully studied based on the specifications of the components.