Author: C Langelier; MS Zinter; K Kalantar; GA Yanik; S Christenson; B Odonovan; C White; M Wilson; A Sapru; CC Dvorak; S Miller; CY Chiu; JL DeRisi
Title: Metagenomic Sequencing Detects Respiratory Pathogens in Hematopoietic Cellular Transplant Patients Document date: 2017_1_24
ID: km0b1z64_54
Snippet: Second, our limited sequencing depth did not yield the human transcriptome coverage that would be desired for robust differential gene expression analyses, although we were able to rigorously evaluate a composite metric of immunity genes. Future larger studies are needed to identify and validate gene classifiers that can distinguish LRTI from non-infectious airway diseases in HCT recipients......
Document: Second, our limited sequencing depth did not yield the human transcriptome coverage that would be desired for robust differential gene expression analyses, although we were able to rigorously evaluate a composite metric of immunity genes. Future larger studies are needed to identify and validate gene classifiers that can distinguish LRTI from non-infectious airway diseases in HCT recipients.
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