Author: Smita Gopinath; Myoungjoo V. Kim; Tasfia Rakib; Patrick W. Wong; Michael van Zandt; Natasha A. Barry; Tsuneyasu Kaisho; Andrew L. Goodman; Akiko Iwasaki
Title: Microbiota-independent antiviral protection conferred by aminoglycoside antibiotics Document date: 2018_1_16
ID: dzorkks5_36
Snippet: The copyright holder for this preprint (which was not peer-reviewed) is the . https://doi.org/10.1101/248617 doi: bioRxiv preprint xylazine intraperitoneally and 20μL of antibiotic administered dropwise into the nasal cavity 457 using a pipet tip. All antibiotics were obtained from Sigma-Aldrich (Darmstadt, Germany). FlowJo software (Tree Star, OR) was used to visualize and analyze cytometry data. Cells 495 populations were analyzed as shown in .....
Document: The copyright holder for this preprint (which was not peer-reviewed) is the . https://doi.org/10.1101/248617 doi: bioRxiv preprint xylazine intraperitoneally and 20μL of antibiotic administered dropwise into the nasal cavity 457 using a pipet tip. All antibiotics were obtained from Sigma-Aldrich (Darmstadt, Germany). FlowJo software (Tree Star, OR) was used to visualize and analyze cytometry data. Cells 495 populations were analyzed as shown in the gating scheme ( Supplementary Fig. 14) . Statistics: Gene expression data was analyzed using unpaired t-tests, assuming unequal 528 standard deviation and correcting for multiple comparisons using the Holm-Sidak 529 correction unless otherwise specified. Graphs depicting disease scores were analyzed 530 using 2-way ANOVA with Holm-Sidak correction for multiple comparisons. Graphs 531 depicting viral titers across a time course of infection were analyzed using 2-way ANOVA 532 with no correction for multiple comparisons (Fisher's LSD) unless otherwise specified. 533
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