Author: Norio Yamamoto; Shutoku Matsuyama; Tyuji Hoshino; Naoki Yamamoto
Title: Nelfinavir inhibits replication of severe acute respiratory syndrome coronavirus 2 in vitro. Document date: 2020_4_8
ID: 662pfa61_8
Snippet: Lopinavir, which has been clinically tested in patients with SARS and COVID-19, blocked SARS-CoV-2 replication at a low concentration range and its SI was relatively high among nine inhibitors (EC 50 = 5.73 µM, CC 50 = 74.44 µM, SI = 12.99) (Fig. 1b, j) ......
Document: Lopinavir, which has been clinically tested in patients with SARS and COVID-19, blocked SARS-CoV-2 replication at a low concentration range and its SI was relatively high among nine inhibitors (EC 50 = 5.73 µM, CC 50 = 74.44 µM, SI = 12.99) (Fig. 1b, j) .
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