Author: Yadi Zhou; Yuan Hou; Jiayu Shen; Yin Huang; William Martin; Feixiong Cheng
Title: Network-based Drug Repurposing for Human Coronavirus Document date: 2020_2_5
ID: b4mdiont_61
Snippet: In conclusion, this study offers a powerful, integrated network-based systems pharmacology methodology for rapid identification of repurposable drugs and drug combinations for the potential treatment of HCoV. Our approach can minimize the translational gap between preclinical testing results and clinical outcomes, which is a significant problem in the rapid development of efficient treatment strategies for the emerging 2019-nCoV outbreak. From a .....
Document: In conclusion, this study offers a powerful, integrated network-based systems pharmacology methodology for rapid identification of repurposable drugs and drug combinations for the potential treatment of HCoV. Our approach can minimize the translational gap between preclinical testing results and clinical outcomes, which is a significant problem in the rapid development of efficient treatment strategies for the emerging 2019-nCoV outbreak. From a translational perspective, if broadly applied, the network tools developed here could help develop effective treatment strategies for other types of virus and human diseases as well.
Search related documents:
Co phrase search for related documents- clinical outcome and drug combination: 1, 2
- clinical outcome and human disease: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22
- clinical outcome and human disease virus: 1, 2
- clinical outcome and potential treatment: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35
- clinical outcome and preclinical testing: 1
- clinical outcome and rapid development: 1, 2, 3, 4, 5, 6
- clinical outcome and rapid identification: 1, 2, 3, 4, 5
- clinical outcome and significant problem: 1, 2, 3, 4
- clinical outcome and translational gap: 1
- clinical outcome and translational perspective: 1
- clinical outcome and treatment strategy: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21
- develop network tool and network tool: 1
- drug combination and human disease: 1, 2, 3, 4
- drug combination and potential treatment: 1, 2, 3, 4, 5, 6
- drug combination and preclinical testing: 1, 2
- drug combination and rapid development: 1, 2, 3, 4
- drug combination and rapid identification: 1, 2
- drug combination and repurposable drug: 1
- drug combination and treatment strategy: 1, 2, 3, 4, 5, 6, 7
Co phrase search for related documents, hyperlinks ordered by date