Selected article for: "clinical testing and preclinical testing"
Author: Yadi Zhou; Yuan Hou; Jiayu Shen; Yin Huang; William Martin; Feixiong Cheng
Title: Network-based Drug Repurposing for Human Coronavirus
  • Document date: 2020_2_5
    • ID: b4mdiont_61
    Snippet: In conclusion, this study offers a powerful, integrated network-based systems pharmacology methodology for rapid identification of repurposable drugs and drug combinations for the potential treatment of HCoV. Our approach can minimize the translational gap between preclinical testing results and clinical outcomes, which is a significant problem in the rapid development of efficient treatment strategies for the emerging 2019-nCoV outbreak. From a .....
    Document: In conclusion, this study offers a powerful, integrated network-based systems pharmacology methodology for rapid identification of repurposable drugs and drug combinations for the potential treatment of HCoV. Our approach can minimize the translational gap between preclinical testing results and clinical outcomes, which is a significant problem in the rapid development of efficient treatment strategies for the emerging 2019-nCoV outbreak. From a translational perspective, if broadly applied, the network tools developed here could help develop effective treatment strategies for other types of virus and human diseases as well.

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