Author: David Brann; Tatsuya Tsukahara; Caleb Weinreb; Darren W. Logan; Sandeep Robert Datta
Title: Non-neural expression of SARS-CoV-2 entry genes in the olfactory epithelium suggests mechanisms underlying anosmia in COVID-19 patients Document date: 2020_3_27
ID: bb4h255w_54
Snippet: To establish a cell type mapping: 1) Durante (44) and Deprez (37) data were combined and gene expression values were linearly scaled so that all cells across datasets had the same total counts. PCA was then performed using highly variable genes (n=1477 genes) and PCAbatch-correction (68) with the Durante data as a reference set. 2) Mapping was then performed bidirectionally between the two datasets. Each cell from "Dataset 1" 'voted' for the 5 mo.....
Document: To establish a cell type mapping: 1) Durante (44) and Deprez (37) data were combined and gene expression values were linearly scaled so that all cells across datasets had the same total counts. PCA was then performed using highly variable genes (n=1477 genes) and PCAbatch-correction (68) with the Durante data as a reference set. 2) Mapping was then performed bidirectionally between the two datasets. Each cell from "Dataset 1" 'voted' for the 5 most similar cells in the "Dataset 2", using distance in PCA space as the measure of similarity. A table T counting votes across cell types was then computed, where for cell type i in the Dataset 1 and cell type j in the Dataset 2,
Search related documents:
Co phrase search for related documents- cell type and gene expression: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79
- cell type and gene expression value: 1, 2
- cell type and highly variable gene: 1
- cell type and set reference: 1
- cell type and similar cell: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46
- cell type and total count: 1, 2, 3
- cell type mapping and dataset cell: 1
- cell type mapping and gene expression: 1
- dataset cell and gene expression: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19
- dataset cell and set reference: 1
- dataset cell and similar cell: 1, 2
- gene expression and highly variable gene: 1, 2, 3, 4
- gene expression and PCA space: 1
- gene expression and set reference: 1, 2, 3, 4, 5, 6
- gene expression and similar cell: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22
- gene expression and similarity measure: 1, 2
- gene expression and total count: 1, 2, 3, 4, 5, 6, 7
Co phrase search for related documents, hyperlinks ordered by date