Selected article for: "coronavirus host range and host range"
Author: Yujun Li; Haimin Wang; Xiaojuan Tang; Danting Ma; Chengzhi Du; Yifei Wang; Hong Pan; Qing Zou; Jie Zheng; Liangde Xu; Michael Farzan; Guocai Zhong
Title: Potential host range of multiple SARS-like coronaviruses and an improved ACE2-Fc variant that is potent against both SARS-CoV-2 and SARS-CoV-1
  • Document date: 2020_4_11
    • ID: dblrxlt1_8
    Snippet: In this study, we found that ACE2 orthologs of a wide range of domestic animals and pangolins 113 efficiently support binding and entry of SARS-CoV-2, as well as that of SARS-CoV-1, a pangolin 114 coronavirus (Pangolin-CoV), and bat coronavirus RaTG13. In addition, the pangolin coronavirus 115 tested here showed the broadest host range. Our data therefore suggest that livestock and companion 116 pets, including camels, cattle, horses, goats, shee.....
    Document: In this study, we found that ACE2 orthologs of a wide range of domestic animals and pangolins 113 efficiently support binding and entry of SARS-CoV-2, as well as that of SARS-CoV-1, a pangolin 114 coronavirus (Pangolin-CoV), and bat coronavirus RaTG13. In addition, the pangolin coronavirus 115 tested here showed the broadest host range. Our data therefore suggest that livestock and companion 116 pets, including camels, cattle, horses, goats, sheep, pigs, cats, and rabbits are potential intermediate 117 hosts for these viruses. Therefore, to prevent new outbreaks of SARS-CoV-2 transmission, it is 118 author/funder. All rights reserved. No reuse allowed without permission.

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