Author: Zheng Zhang; Sifan Ye; Aiping Wu; Taijiao Jiang; Yousong Peng
Title: Prediction of receptorome for human-infecting virome Document date: 2020_2_28
ID: 9ruhvpbv_32
Snippet: The RF model based on combination of 20 amino-acid frequencies achieved an AUC 0.68. When using the frequencies of k-mers with two amino acids as features, only the top N (N=1 to 400) most important features were used in the modeling to reduce over-fitting. Figure S1 showed that the AUC of the RF models increased rapidly as increase of N from 1 to 10. Then, it increased slowly or even decreased when more ten features were used. Therefore, only to.....
Document: The RF model based on combination of 20 amino-acid frequencies achieved an AUC 0.68. When using the frequencies of k-mers with two amino acids as features, only the top N (N=1 to 400) most important features were used in the modeling to reduce over-fitting. Figure S1 showed that the AUC of the RF models increased rapidly as increase of N from 1 to 10. Then, it increased slowly or even decreased when more ten features were used. Therefore, only top ten features were used in the modeling to balance the model performance and complexity. The RF model based on top ten features achieved an AUC of 0.72.
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