Author: Brandon Michael Henry; Maria Helena S Oliveira
Title: Preliminary epidemiological analysis on children and adolescents with novel coronavirus disease 2019 outside Hubei Province, China: an observational study utilizing crowdsourced data Document date: 2020_3_6
ID: j58f1lwa_36
Snippet: The mild nature of pediatric cases is likely multifactorial. Age related differences in innate immunity 13,14 , in which monocytes and macrophages may play an important role controlling an emerging viral pathogen, may be partially responsible for the milder observed symptoms and asymptomatic cases. Others have suggested that respiratory tract health, including less exposure to pollution, as well as lung epithelial cell senescence and immunosenesc.....
Document: The mild nature of pediatric cases is likely multifactorial. Age related differences in innate immunity 13,14 , in which monocytes and macrophages may play an important role controlling an emerging viral pathogen, may be partially responsible for the milder observed symptoms and asymptomatic cases. Others have suggested that respiratory tract health, including less exposure to pollution, as well as lung epithelial cell senescence and immunosenescence of immune cells of the respiratory system may play a role. 15 Cai et al. reported that while COVID-19 viral shredding in respiratory specimens is longer in children than adults and also observed in the stool specimens, . CC-BY-NC-ND 4.0 International license It is made available under a author/funder, who has granted medRxiv a license to display the preprint in perpetuity.
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