Author: Haoyan Chen; Baoqin Xuan; Yuqing Yan; Xiaoqiang Zhu; Chaoqin Shen; Gang Zhao; Linhua Ji; Danhua Xu; Hua Xiong; TaChung Yu; Xiaobo Li; Qiang Liu; Yingxuan Chen; Yun Cui; Jie Hong; Jing-Yuan Fang
Title: Profiling ACE2 expression in colon tissue of healthy adults and colorectal cancer patients by single-cell transcriptome analysis Document date: 2020_2_23
ID: 3r0nqzgu_15
Snippet: The upper respiratory, gastrointestinal and central nervous system are usually the infection targets of coronavirus in humans and other mammals(11). A distinct coronavirus SARS-CoV was identified as the etiological agent of severe acute respiratory syndrome (SARS) (2, 12, 13) . This virus may destroy the upper respiratory tract and damage the patient's intestines by causing diarrhea (14) (15) (16) . In December 2019, 2019-nCoV from the same famil.....
Document: The upper respiratory, gastrointestinal and central nervous system are usually the infection targets of coronavirus in humans and other mammals(11). A distinct coronavirus SARS-CoV was identified as the etiological agent of severe acute respiratory syndrome (SARS) (2, 12, 13) . This virus may destroy the upper respiratory tract and damage the patient's intestines by causing diarrhea (14) (15) (16) . In December 2019, 2019-nCoV from the same family as SARS virus has been identified, and this virus can also cause fever, lower respiratory tract infection and gastrointestinal symptoms (17) . The genome sequences of 2019-nCoV have been obtained by next-generation sequencing from pneumonia disease patients' samples, and the spike protein of this virus was identified as well (17) . This virus may directly bind the . CC-BY-NC-ND 4.0 International license It is made available under a is the author/funder, who has granted medRxiv a license to display the preprint in perpetuity.
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