Author: Han Suh Kang; Katelyn McNair; Daniel A. Cuevas; Barbara A. Bailey; Anca M. Segall; Robert A. Edwards
Title: Prophage genomics reveals patterns in phage genome organization and replication Document date: 2017_3_7
ID: 0abutzb3_42
Snippet: We identified the fourteen most commonly occurring and well-annotated genes within the prophage dataset (Table 1 ). The majority (66.9%; 10,542/15,765) of these predicted prophages had the integrase gene located near one of the ends of the prophage genome. We generated a genome data set where all the genomes were organized with the integrase at the same end of the genome, in some cases by reverse-complementing the genome to place the integrase ge.....
Document: We identified the fourteen most commonly occurring and well-annotated genes within the prophage dataset (Table 1 ). The majority (66.9%; 10,542/15,765) of these predicted prophages had the integrase gene located near one of the ends of the prophage genome. We generated a genome data set where all the genomes were organized with the integrase at the same end of the genome, in some cases by reverse-complementing the genome to place the integrase gene consistently at the left end of every genome, and in other cases by recircularizing the genome in silico and introducing a break that placed the integrase at the left end.
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