Author: Yafei Wang; Randy Heiland; Morgan Craig; Courtney L. Davis; Ashlee N Ford Versypt; Adrianne Jenner; Jonathan Ozik; Nicholson Collier; Chase Cockrell; Andrew Becker; Gary An; James A. Glazier; Aarthi Narayanan; Amber M Smith; Paul Macklin
Title: Rapid community-driven development of a SARS-CoV-2 tissue simulator Document date: 2020_4_5
ID: lq4tcyh4_136
Snippet: We model these dynamics of internalized virions through a simplified system of ODEs: In this proof of concept prototype, we modeled apoptotic response to cell disruption but did not model interferon processes. As a simplification, we modeled cell disruption as correlated with assembled virions A, and we used a Hill pharmacodynamic model to relate the cell's apoptosis rate to A:.....
Document: We model these dynamics of internalized virions through a simplified system of ODEs: In this proof of concept prototype, we modeled apoptotic response to cell disruption but did not model interferon processes. As a simplification, we modeled cell disruption as correlated with assembled virions A, and we used a Hill pharmacodynamic model to relate the cell's apoptosis rate to A:
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