Selected article for: "bacterial infection and secondary bacterial infection"
Author: Aran Singanayagam; Su-Ling Loo; Maria Calderazzo; Lydia J Finney; Maria-Belen Trujillo Torralbo; Eteri Bakhsoliani; Jason Girkin; Punnam Veerati; Prabuddha S Pathinayake; Kristy S Nichol; Andrew Reid; Joseph Foottit; Sebastian L Johnston; Nathan W Bartlett; Patrick Mallia
Title: Anti-microbial immunity is impaired in COPD patients with frequent exacerbations
  • Document date: 2019_5_9
    • ID: 72jzqm86_31
    Snippet: Virus-induced exacerbation can trigger subsequent bacterial infection in COPD 12, 13 , a secondary phenomenon that is associated with increased exacerbation severity 12 and inversely related to the interferon responses 21 . Having observed that anti-viral immunity is reduced in frequent exacerbators both in vivo and primary BECs from patients with COPD in vitro, we next examined whether sputum bacterial loads at stable state and during exacerbati.....
    Document: Virus-induced exacerbation can trigger subsequent bacterial infection in COPD 12, 13 , a secondary phenomenon that is associated with increased exacerbation severity 12 and inversely related to the interferon responses 21 . Having observed that anti-viral immunity is reduced in frequent exacerbators both in vivo and primary BECs from patients with COPD in vitro, we next examined whether sputum bacterial loads at stable state and during exacerbation differed according to exacerbation frequency.

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