Selected article for: "Influenza virus and respiratory disease"

Author: Salman L. Butt; Eric C. Erwood; Jian Zhang; Holly S. Sellers; Kelsey Young; Kevin K. Lahmers; James B. Stanton
Title: Real-time, MinION-based, amplicon sequencing for lineage typing of infectious bronchitis virus from upper respiratory samples
  • Document date: 2019_5_10
  • ID: hxmk6gvr_1
    Snippet: Infectious bronchitis (IB), which is caused by infectious bronchitis virus (IBV), is one of the most important diseases of poultry, causing severe economic losses worldwide. 8 Clinical signs of disease are diverse and include respiratory distress, severe ocular discharge, poor body weight gain, decreased egg production, flushing (renal disease), and occasionally mortality in chickens. 7 IB is often complicated by secondary bacterial (e.g., E. col.....
    Document: Infectious bronchitis (IB), which is caused by infectious bronchitis virus (IBV), is one of the most important diseases of poultry, causing severe economic losses worldwide. 8 Clinical signs of disease are diverse and include respiratory distress, severe ocular discharge, poor body weight gain, decreased egg production, flushing (renal disease), and occasionally mortality in chickens. 7 IB is often complicated by secondary bacterial (e.g., E. coli, Mycoplasma sp.) and viral infections (e.g., avian influenza virus, Newcastle disease virus, and infectious laryngotracheitis virus). 43 Lack of cross protection among IBV serotypes is a challenge to controlling IB 15 ; therefore, control of IB relies heavily on serotype-specific live attenuated vaccines. 8 Collectively, the presence of multiple IBVs in a single sample, emergence of variant IBVs, and the high genetic diversity of IBV can complicate the diagnosis of IB and illustrate the need for enhanced diagnostics. 15

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