Author: James Bull; Scott L. Nuismer; Rustom Antia
Title: Recombinant vector vaccines and within-host evolution Document date: 2019_2_8
ID: 3vssgben_42
Snippet: 2. Acute infections. Infections are short term because they are subject to control and clearance by any 424 combination of three factors: resource limitation, innate immunity and adaptive immunity. Further 425 details not included in this Appendix can be found in Supplements. The following Adaptive immunity s rate of clonal expansion of adaptive immunity 3 φ X antigen for half max growth of adaptive immunity X 10 3 φ Y antigen for half max grow.....
Document: 2. Acute infections. Infections are short term because they are subject to control and clearance by any 424 combination of three factors: resource limitation, innate immunity and adaptive immunity. Further 425 details not included in this Appendix can be found in Supplements. The following Adaptive immunity s rate of clonal expansion of adaptive immunity 3 φ X antigen for half max growth of adaptive immunity X 10 3 φ Y antigen for half max growth of adaptive immunity Y 10 3 k X killing rate of V due to X (immunity to insert) 10 −6 , various k Y killing rate of V & W due to Y (immunity to vector) 10 −6 , various
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