Author: Aran Singanayagam; Su-Ling Loo; Maria Calderazzo; Lydia J Finney; Maria-Belen Trujillo Torralbo; Eteri Bakhsoliani; Jason Girkin; Punnam Veerati; Prabuddha S Pathinayake; Kristy S Nichol; Andrew Reid; Joseph Foottit; Sebastian L Johnston; Nathan W Bartlett; Patrick Mallia
Title: Anti-microbial immunity is impaired in COPD patients with frequent exacerbations Document date: 2019_5_9
ID: 72jzqm86_7
Snippet: Subjects then had repeat visits at three monthly intervals when clinically stable and were followed up for a minimum of 6 months. Subjects reported to the study team when they developed symptoms of an upper respiratory tract infection or an increase in any of the symptoms of dyspnoea, cough, sputum volume or purulence. Exacerbation was defined using the East London cohort criteria. 2 Subjects were seen within 48 hours of onset of their symptoms f.....
Document: Subjects then had repeat visits at three monthly intervals when clinically stable and were followed up for a minimum of 6 months. Subjects reported to the study team when they developed symptoms of an upper respiratory tract infection or an increase in any of the symptoms of dyspnoea, cough, sputum volume or purulence. Exacerbation was defined using the East London cohort criteria. 2 Subjects were seen within 48 hours of onset of their symptoms for collection of samples and repeat visits was carried out a two weeks after the initial exacerbation visit. Samples from this cohort have been used in a previous study investigating the role of airway glucose in COPD 17
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