Author: Lijiao Zeng; Jialu Li; Mingfeng Liao; Rui Hua; Pilai Huang; Mingxia Zhang; Youlong Zhang; Qinlang Shi; Zhaohua Xia; Xinzhong Ning; Dandan Liu; Jiu Mo; Ziyuan Zhou; Zigang Li; Yu Fu; Yuhui Liao; Jing Yuan; Lifei Wang; Qing He; Lei Liu; Kun Qiao
Title: Risk assessment of progression to severe conditions for patients with COVID-19 pneumonia: a single-center retrospective study Document date: 2020_3_30
ID: 8n3q30hy_15
Snippet: The severe group has a significantly lower number of platelet and lymphocytes but increased levels of coagulation function indicators such as fibrinogen, d-dimer and activated partial thromboplastin time. As for blood biochemistry, the biomarkers with a significantly increased level in severe group as compared to that of non-severe group include lactate dehydrogenase, myoglobin, aspartate transaminase, mitochondrial-aspartate transaminase, creati.....
Document: The severe group has a significantly lower number of platelet and lymphocytes but increased levels of coagulation function indicators such as fibrinogen, d-dimer and activated partial thromboplastin time. As for blood biochemistry, the biomarkers with a significantly increased level in severe group as compared to that of non-severe group include lactate dehydrogenase, myoglobin, aspartate transaminase, mitochondrial-aspartate transaminase, creatine kinase myocardial band, troponin I, N-terminal brain natriuretic peptide, γ -glutamyl transpeptidase and alpha-hydroxybutyrate dehydrogenase, while those with decreased levels include albumin and prealbumin. For the infection-related biomarkers, we observed a significant increase in C-reactive protein, interleukin-6, procalcitonin and erythrocyte sedimentation rate in severe group, all of which have a mean level beyond the upper bound of normal reference. We also observed an abnormal level of blood oxygen like PaO2/FiO2 ratio and kidney function indicators including All rights reserved. No reuse allowed without permission.
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