Author: Denisa Bojkova; Jake E. McGreig; Katie-May McLaughlin; Stuart G. Masterson; Marek Widera; Verena Krähling; Sandra Ciesek; Mark N. Wass; Martin Michaelis; Jindrich Cinatl
Title: SARS-CoV-2 and SARS-CoV differ in their cell tropism and drug sensitivity profiles Document date: 2020_4_5
ID: gpr86lxe_35
Snippet: both SARS-CoV-2 and SARS-CoV CPE formation. In contrast to aprotinin, camostat, 429 . CC-BY-NC-ND 4.0 International license author/funder. It is made available under a The copyright holder for this preprint (which was not peer-reviewed) is the . https://doi.org/10.1101/2020.04.03.024257 doi: bioRxiv preprint and nafamostat exerted limited activity against double-stranded RNA formation in 430 SARS-CoV-2-infected cells. This may indicate that camos.....
Document: both SARS-CoV-2 and SARS-CoV CPE formation. In contrast to aprotinin, camostat, 429 . CC-BY-NC-ND 4.0 International license author/funder. It is made available under a The copyright holder for this preprint (which was not peer-reviewed) is the . https://doi.org/10.1101/2020.04.03.024257 doi: bioRxiv preprint and nafamostat exerted limited activity against double-stranded RNA formation in 430 SARS-CoV-2-infected cells. This may indicate that camostat and nafamostat rather 431 exert cytoprotective effects that prevent cells from virus-induced lysis but less 432 pronounced antiviral activity. The mechanisms underlying the enhanced anti-SARS-433
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