Selected article for: "II MHC Class epitope and MHC Class II epitope"

Author: Neha Jain; Uma Shankar; Prativa Majee; Amit Kumar
Title: Scrutinizing the SARS-CoV-2 protein information for the designing an effective vaccine encompassing both the T-cell and B-cell epitopes
  • Document date: 2020_4_1
  • ID: lmstdmyb_21
    Snippet: The MHC class I ad class II molecules were downloaded from RCSB PDB database (https://www.rcsb.org/). Those that were not available were in PDB database were retrieved from pHLA database (https://www.phla3d.com.br/) [42] . The structures of the SARS-CoV-2 proteins were constructed using I-TASSER (https://zhanglab.ccmb.med.umich.edu/I-TASSER/) [43] and HTL and CTL epitopes were mapped and their structures were retrieved using PyMol tool. For the m.....
    Document: The MHC class I ad class II molecules were downloaded from RCSB PDB database (https://www.rcsb.org/). Those that were not available were in PDB database were retrieved from pHLA database (https://www.phla3d.com.br/) [42] . The structures of the SARS-CoV-2 proteins were constructed using I-TASSER (https://zhanglab.ccmb.med.umich.edu/I-TASSER/) [43] and HTL and CTL epitopes were mapped and their structures were retrieved using PyMol tool. For the molecular interaction analysis of the predicted best HLA-epitope pairs for both MHC class I and class II alleles, ClusPro protein-protein docking tool (https://cluspro.org/login.php) [44] was utilized.

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