Selected article for: "CTL epitope and HTL CTL epitope"

Author: Neha Jain; Uma Shankar; Prativa Majee; Amit Kumar
Title: Scrutinizing the SARS-CoV-2 protein information for the designing an effective vaccine encompassing both the T-cell and B-cell epitopes
  • Document date: 2020_4_1
  • ID: lmstdmyb_25
    Snippet: For constructing a multi-epitope vaccine construct, the selected best HTL, CTL and B-cell epitopes were joined by using GPGPG, AAG and KK linkers respectively. For the better immunogenic response, four adjuvants namely, β-defensin, universal memory T cell helper peptide (TpD), PADRE sequence and a M cell ligand were added by using EAAAK linker into the vaccine construct......
    Document: For constructing a multi-epitope vaccine construct, the selected best HTL, CTL and B-cell epitopes were joined by using GPGPG, AAG and KK linkers respectively. For the better immunogenic response, four adjuvants namely, β-defensin, universal memory T cell helper peptide (TpD), PADRE sequence and a M cell ligand were added by using EAAAK linker into the vaccine construct.

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