Author: Ramasubramanian Sundaramoorthy; Amanda L. Hughes; Hassane El-Mkami; David Norman; Tom Owen-Hughes
Title: Structure of the chromatin remodelling enzyme Chd1 bound to a ubiquitinylated nucleosome Document date: 2018_3_30
ID: ct2zhauz_16
Snippet: The repositioning of the chromodomains in turn acts as a lever to reposition the DNA binding domain. In the context of nucleosomes this results in nucleotide dependent unwrapping of two turns of nucleosomal DNA (Sundaramoorthy et al., 2017) . Conversely, the interaction of the DNABD requires linker DNA to be accessible......
Document: The repositioning of the chromodomains in turn acts as a lever to reposition the DNA binding domain. In the context of nucleosomes this results in nucleotide dependent unwrapping of two turns of nucleosomal DNA (Sundaramoorthy et al., 2017) . Conversely, the interaction of the DNABD requires linker DNA to be accessible.
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