Selected article for: "preparation process and sample preparation process"
Author: Yichun Wang; Usha Kadiyala; Zhibei Qu; Paolo Elvati; Christopher Altheim; Nicholas A. Kotov; Angela Violi; J. Scott VanEpps
Title: Anti-biofilm Activity of Graphene Quantum Dots via Self-Assembly with Bacterial Amyloid Proteins
  • Document date: 2019_2_19
    • ID: e0sxynb1_9
    Snippet: The structural changes of amyloid-rich biofilms before and after GQD (500 µg/mL) treatment was further verified by scanning electron microscopy (SEM) (Figure 1i, j) . Here the change in porosity of the PNG biofilm is even more distinct than that in confocal microscopy, which increased to 71.2 ± 6.6 % (Figure 1k) . This is likely a result of dehydration process required for SEM sample preparation, which washed off weakly attached bacterial cells.....
    Document: The structural changes of amyloid-rich biofilms before and after GQD (500 µg/mL) treatment was further verified by scanning electron microscopy (SEM) (Figure 1i, j) . Here the change in porosity of the PNG biofilm is even more distinct than that in confocal microscopy, which increased to 71.2 ± 6.6 % (Figure 1k) . This is likely a result of dehydration process required for SEM sample preparation, which washed off weakly attached bacterial cells and loose ECM content. The phenomenon not only confirmed the increase of biofilm porosity after GQD treatment but also indicated reduced integrity of remaining biomass.

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