Selected article for: "bacterial infection and COPD airway"
Author: Aran Singanayagam; Su-Ling Loo; Maria Calderazzo; Lydia J Finney; Maria-Belen Trujillo Torralbo; Eteri Bakhsoliani; Jason Girkin; Punnam Veerati; Prabuddha S Pathinayake; Kristy S Nichol; Andrew Reid; Joseph Foottit; Sebastian L Johnston; Nathan W Bartlett; Patrick Mallia
Title: Anti-microbial immunity is impaired in COPD patients with frequent exacerbations
  • Document date: 2019_5_9
    • ID: 72jzqm86_55
    Snippet: In conclusion, we show that patients with COPD and a history of frequent exacerbations have reduced anti-viral and anti-bacterial immunity associated with increased secondary bacterial infection. These immune defects may underlie the increased propensity to exacerbations observed in this sub-group and provides evidence to support therapeutic approaches that boost innate immunity in COPD author/funder. All rights reserved. No reuse allowed without.....
    Document: In conclusion, we show that patients with COPD and a history of frequent exacerbations have reduced anti-viral and anti-bacterial immunity associated with increased secondary bacterial infection. These immune defects may underlie the increased propensity to exacerbations observed in this sub-group and provides evidence to support therapeutic approaches that boost innate immunity in COPD author/funder. All rights reserved. No reuse allowed without permission. Table 3 : Baseline characteristics of patients with COPD undergoing bronchoscopic sampling for airway epithelial cell experiments shown in figure 5.

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