Author: Rafael R. de Assis; Aarti Jain; Rie Nakajima; Algis Jasinskas; Jiin Felgner; Joshua M. Obiero; Oluwasanmi Adenaiye; Sheldon Tai; Filbert Hong; Philip Norris; Mars Stone; Graham Simmons; Anil Bagri; Martin Schreiber; Andreas Buser; Andreas Holbro; Manuel Battegay; Donald K. Milton; Huw Davies; Laurence M. Corash; Michael P. Busch; Philip L. Felgner; Saahir Khan
Title: Analysis of SARS-CoV-2 Antibodies in COVID-19 Convalescent Plasma using a Coronavirus Antigen Microarray Document date: 2020_4_17
ID: ax9btc74_16
Snippet: A coronavirus antigen microarray containing a panel of antigens from SARS-CoV-2 in addition to other human coronaviruses was able to reliably distinguish convalescent plasma of PCR-positive COVID-19 cases from negative control sera collected prior to the pandemic by detecting both strain-specific and cross-reactive antibodies. Further studies are needed to apply this methodology to large-scale serologic surveillance studies and to correlate speci.....
Document: A coronavirus antigen microarray containing a panel of antigens from SARS-CoV-2 in addition to other human coronaviruses was able to reliably distinguish convalescent plasma of PCR-positive COVID-19 cases from negative control sera collected prior to the pandemic by detecting both strain-specific and cross-reactive antibodies. Further studies are needed to apply this methodology to large-scale serologic surveillance studies and to correlate specific antibody responses with clinical outcomes.
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