Author: Bishajit Sarkar; Md. Asad Ullah; Fatema Tuz Johora; Masuma Afrin Taniya; Yusha Araf
Title: The Essential Facts of Wuhan Novel Coronavirus Outbreak in China and Epitope-based Vaccine Designing against COVID-19 Document date: 2020_2_11
ID: 7vrm081c_73
Snippet: vaccine. The vaccine construct with the best result in the molecular docking, was considered as the best vaccine construct. According to docking results, it was found that CV-1 was the best constructed vaccine. CV-1 showed the best and lowest scores in the docking as well as in the MM-GBSA study. However, CV-2 showed the best binding affinity (ΔG scores) with DRB3*0202 (- showed the best results in the protein-protein docking study, it was consi.....
Document: vaccine. The vaccine construct with the best result in the molecular docking, was considered as the best vaccine construct. According to docking results, it was found that CV-1 was the best constructed vaccine. CV-1 showed the best and lowest scores in the docking as well as in the MM-GBSA study. However, CV-2 showed the best binding affinity (ΔG scores) with DRB3*0202 (- showed the best results in the protein-protein docking study, it was considered as the best vaccine construct among the three constructed vaccines (Figure 09 & Table 15 ). Later, the molecular dynamics simulation study and in silico codon adaptation studies were conducted only on the CV-1 vaccine. The copyright holder for this preprint (which was not peer-reviewed) is the . https://doi.org/10.1101/2020.02.05.935072 doi: bioRxiv preprint
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