Author: Bishajit Sarkar; Md. Asad Ullah; Fatema Tuz Johora; Masuma Afrin Taniya; Yusha Araf
Title: The Essential Facts of Wuhan Novel Coronavirus Outbreak in China and Epitope-based Vaccine Designing against COVID-19 Document date: 2020_2_11
ID: 7vrm081c_91
Snippet: The SARS-CoV-2 has caused one of the deadliest outbreaks in the recent times. Prevention of the newly emerging infection is very challenging as well as mandatory. The potentiality of in silico methods can be exploited to find desired solutions with fewer trials and errors and thus saving both time and costs of the scientists. In this study, potential subunit vaccines were designed against the SARS-CoV-2 using various methods of reverse vaccinolog.....
Document: The SARS-CoV-2 has caused one of the deadliest outbreaks in the recent times. Prevention of the newly emerging infection is very challenging as well as mandatory. The potentiality of in silico methods can be exploited to find desired solutions with fewer trials and errors and thus saving both time and costs of the scientists. In this study, potential subunit vaccines were designed against the SARS-CoV-2 using various methods of reverse vaccinology and immunoinformatics. To design the vaccines, the highly antigenic viral proteins as well as epitopes were used. Various computational studies of the suggested vaccine constructs revealed that these vaccines might confer good immunogenic response. For this reason, if satisfactory results are achieved in various in vivo and in vitro tests and trials, these suggested vaccine constructs might be used effectively for vaccination to prevent the coronavirus infection and spreading. Therefore, our present study should help the scientists to develop potential vaccines and therapeutics against the Wuhan Novel Coronavirus 2019. Authors declare no conflict of interest regarding the publication of the manuscript.
Search related documents:
Co phrase search for related documents- computational study and cost time: 1, 2, 3
- computational study and deadly outbreak: 1
- computational study and immunogenic response: 1
- computational study and potential vaccine: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10
- computational study and present study: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40
- computational study and reverse vaccinology: 1
- computational study and vaccine construct: 1, 2, 3, 4, 5, 6
- computational study and vaccine design: 1, 2, 3, 4, 5, 6, 7, 8, 9
- computational study and viral protein: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19
- coronavirus infection and cost time: 1, 2, 3, 4, 5, 6, 7, 8, 9
- coronavirus infection and deadly outbreak: 1, 2
- coronavirus infection and immunogenic response: 1
- coronavirus infection and interest conflict: 1, 2, 3
- coronavirus infection and manuscript publication: 1
- coronavirus infection and potential vaccine: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22
- coronavirus infection and present study: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73
- coronavirus infection and recent time: 1, 2, 3, 4, 5, 6, 7, 8
- coronavirus infection and reverse vaccinology: 1, 2
- coronavirus infection and subunit vaccine: 1, 2, 3, 4
Co phrase search for related documents, hyperlinks ordered by date