Author: Kunihiro Matsushita; Ning Ding; Minghao Kou; Xiao Hu; Mengkun Chen; Yumin Gao; Yasuyuki Honda; David Dowdy; Yejin Mok; Junichi Ishigami; Lawrence J Appel
Title: The relationship of COVID-19 severity with cardiovascular disease and its traditional risk factors: A systematic review and meta-analysis Document date: 2020_4_7
ID: 4mnmaky6_27
Snippet: Meta-regression analyses demonstrated that studies with greater age difference between those with vs. without severe COVID-19 tended to have greater relative risk according to the presence of hypertension, diabetes, and pre-existing CVD, indicating some levels of potential confounding by age (Figure 4) , although none of the analyses reached statistical significance. A similar pattern was seen for CVD and the difference in the proportion of male .....
Document: Meta-regression analyses demonstrated that studies with greater age difference between those with vs. without severe COVID-19 tended to have greater relative risk according to the presence of hypertension, diabetes, and pre-existing CVD, indicating some levels of potential confounding by age (Figure 4) , although none of the analyses reached statistical significance. A similar pattern was seen for CVD and the difference in the proportion of male sex between those with vs. without severe COVID-19 (Web Figure 3) . On the other hand, meta-. CC-BY-NC-ND 4.0 International license It is made available under a author/funder, who has granted medRxiv a license to display the preprint in perpetuity.
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