Author: Takako I. Jones; Guo-Liang Chew; Pamela Barraza-Flores; Spencer Schreier; Monique Ramirez; Ryan D. Wuebbles; Dean J. Burkin; Robert K. Bradley; Peter L. Jones
Title: Transgenic mice expressing tunable levels of DUX4 develop characteristic facioscapulohumeral muscular dystrophy-like pathophysiology ranging in severity Document date: 2018_11_15
ID: 1yto01tr_53
Snippet: Interestingly, the mild model bi-transgenic mice, which have low mosaic expression of DUX4-FL, similarly showed no detectable expression of eMyHC ( Figure 11K , L, S, T), indicating that myofibers with centralized nuclei in the mild model are remnants of an old regeneration event......
Document: Interestingly, the mild model bi-transgenic mice, which have low mosaic expression of DUX4-FL, similarly showed no detectable expression of eMyHC ( Figure 11K , L, S, T), indicating that myofibers with centralized nuclei in the mild model are remnants of an old regeneration event.
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