Author: Xavier Hernandez-Alias; Martin Schaefer; Luis Serrano
Title: Translational adaptation of human viruses to the tissues they infect Document date: 2020_4_7
ID: 0rk2dw4e_48
Snippet: As described by dos Reis et al. (2003, 2004) , the tAI weights every codon based on the wobble-base codon-anticodon interaction rules. Let be a codon, then the decoding weight is a weighted sum of the square-root-normalized tRNA abundances for all tRNA isoacceptors that bind with affinity The SDA aims to consider not only tRNA abundances, but also the codon usage demand. In doing so, it constitutes a global measure of translation control, since t.....
Document: As described by dos Reis et al. (2003, 2004) , the tAI weights every codon based on the wobble-base codon-anticodon interaction rules. Let be a codon, then the decoding weight is a weighted sum of the square-root-normalized tRNA abundances for all tRNA isoacceptors that bind with affinity The SDA aims to consider not only tRNA abundances, but also the codon usage demand. In doing so, it constitutes a global measure of translation control, since the efficiency of a certain . CC-BY 4.0 International license author/funder. It is made available under a The copyright holder for this preprint (which was not peer-reviewed) is the . https://doi.org/10.1101/2020.04.06.027557 doi: bioRxiv preprint codon depends both on its complementary anticodon abundance as well as the demand for such anticodon by other transcripts. This global control has been indeed established to play an important role in defining optimal translation programs 63 .
Search related documents:
Co phrase search for related documents- affinity bind and square root: 1
- anticodon demand and codon anticodon: 1
- anticodon demand and codon usage demand: 1
- global control and important role: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10
- global control and square root: 1
- global measure and important role: 1
- global measure and square root: 1
Co phrase search for related documents, hyperlinks ordered by date