Selected article for: "small sample and study limitation"

Author: Daniel Bean; Zeljko Kraljevic; Thomas Searle; Rebecca Bendayan; Andrew Pickles; Amos Folarin; Lukasz Roguski; Kawsar Noor; Anthony Shek; Kevin o'gallagher; Rosita Zakeri; Ajay Shah; James Teo; Richard JB Dobson
Title: Treatment with ACE-inhibitors is associated with less severe disease with SARS-Covid-19 infection in a multi-site UK acute Hospital Trust
  • Document date: 2020_4_11
  • ID: 60wcvkbn_20
    Snippet: One limitation with this study is the relatively small sample taken from a single UK centre over a short follow-up. Although we have used statistical procedures to provide robust results with our current sample, as numbers increase further updates to the analysis will be required to better understand our findings and confirm the directionality of these associations. Our group will provide regular updates during the pandemic to the analysis at the.....
    Document: One limitation with this study is the relatively small sample taken from a single UK centre over a short follow-up. Although we have used statistical procedures to provide robust results with our current sample, as numbers increase further updates to the analysis will be required to better understand our findings and confirm the directionality of these associations. Our group will provide regular updates during the pandemic to the analysis at the link https://cogstack.org/cogstack-kch-covid-19-analyses/ including longer follow-up and pooled analysis with other organisations. Whether these results also apply to infection severity in the non-hospital setting or to different global populations requires further study.

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