Author: Alejandro A Schäffer; Eneida Hatcher; Linda Yankie; Lara Shonkwiler; J Rodney Brister; Ilene Karsch-Mizrachi; Eric P Nawrocki
Title: VADR: validation and annotation of virus sequence submissions to GenBank Document date: 2019_11_22
ID: besvz92f_5
Snippet: Software for viral genome annotation Several software packages exist for viral genome annotation. VAPiD [7] is designed to simplify the submission of complete viral genome sequences to GenBank by adding metadata, and annotating each input sequence based on comparison with its best-matching reference sequence in a large reference dataset derived from GenBank. VIGOR [8, 9] annotates input sequences by first identifying the most relevant reference d.....
Document: Software for viral genome annotation Several software packages exist for viral genome annotation. VAPiD [7] is designed to simplify the submission of complete viral genome sequences to GenBank by adding metadata, and annotating each input sequence based on comparison with its best-matching reference sequence in a large reference dataset derived from GenBank. VIGOR [8, 9] annotates input sequences by first identifying the most relevant reference database in its collection and then comparing all reference protein and mature peptide sequences in that database to the input sequence to determine its annotation and to identify certain types of errors. Both programs detect and report some types of unexpected errors, such as premature stop codons.
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