Viral fitness predicts the magnitude and direction of perturbations in the infected host transcriptome

Héctor Cervera; Silvia Ambrós; Guillermo P. Bernet; Guillermo Rodrigo; Santiago F. Elena

Similarly, A. thaliana plants infected either with a mild or a virulent isolate of turnip mosaic potyvirus (TuMV) also showed profound differences in the genes and functional categories altered 67 . In this case, the more virulent strain mainly altered stress responses and transport functions compared to the mild one 67 . In a recent study, the transcriptomic alterations induced in Nicotiana benthamiana plants infected either with a wild-type tobacco vein banding mosaic potyvirus (TVBMV) or a genotype deficient in VSR protein HC-Pro were compared 68 . Both transcriptomes differed in many aspects, including repression of photosynthesis-related genes, . CC-BY-NC-ND 4.0 International license author/funder. It is made available under a The copyright holder for this preprint (which was not peer-reviewed) is the . https://doi.org/10.1101/206789 doi: bioRxiv preprint genes involved in the RNA silencing pathway, the JA signaling pathway, and the auxin signaling transduction 68 .