Selected article for: "active viral infection and lung tissue"
Author: Sha Fu; Xiaoyu Fu; Yang Song; Min Li; Pin-hua Pan; Tao Tang; Chunhu Zhang; Tiejian Jiang; Deming Tan; Xuegong Fan; Xinping Sha; Jingdong Ma; Yan Huang; Shaling Li; Yixiang Zheng; Zhaoxin Qian; Zeng Xiong; Lizhi Xiao; Huibao Long; Jianghai Chen; Yi Ouyang
Title: Virologic and clinical characteristics for prognosis of severe COVID-19: a retrospective observational study in Wuhan, China
  • Document date: 2020_4_6
    • ID: 4989atst_36
    Snippet: reported that the SARS-CoV-2 infection could initiate increased secretion of Thelper-2 (Th2) cytokines (e.g., IL4 and IL10) that suppress inflammation 18 . In this study, it was also found that severe patients with poor recovery had higher levels of IL-4 compared to patients with good recovery. Since the IL-4 levels were slightly elevated in these patients, it was speculated that this might be due to the antagonistic effects of IL-4 during the ac.....
    Document: reported that the SARS-CoV-2 infection could initiate increased secretion of Thelper-2 (Th2) cytokines (e.g., IL4 and IL10) that suppress inflammation 18 . In this study, it was also found that severe patients with poor recovery had higher levels of IL-4 compared to patients with good recovery. Since the IL-4 levels were slightly elevated in these patients, it was speculated that this might be due to the antagonistic effects of IL-4 during the active phase of the pro-inflammatory response. Importantly, it was found that the wave of the cytokine storm typically occurred during the active phase of viral infection, and a prolonged inflammatory response could be observed in severe patients with poor recovery. Consequently, excessive inflammation damages lung tissue, and subsequent lung repair and regeneration could be initiated. In this All rights reserved. No reuse allowed without permission. the author/funder, who has granted medRxiv a license to display the preprint in perpetuity.

    Search related documents:
    Co phrase search for related documents
    • active phase and good recovery: 1
    • active phase and inflammatory response: 1, 2, 3, 4
    • active phase and poor recovery: 1
    • antagonistic effect and inflammatory response: 1
    • cytokine storm and excessive inflammation damage: 1
    • cytokine storm and good recovery: 1
    • cytokine storm and high level: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
    • cytokine storm and increase secretion: 1, 2, 3
    • cytokine storm and inflammation damage: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
    • cytokine storm and inflammatory response: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
    • cytokine storm and lung repair: 1, 2, 3, 4, 5, 6, 7
    • cytokine storm and lung tissue: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
    • excessive inflammation damage and inflammation damage: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19
    • excessive inflammation damage and inflammatory response: 1, 2, 3, 4, 5
    • excessive inflammation damage and lung tissue: 1
    • good recovery and inflammatory response: 1, 2, 3
    • good recovery and lung tissue: 1, 2
    • good recovery and poor recovery: 1, 2, 3, 4, 5, 6, 7
    • good recovery patient and inflammatory response: 1