Selected article for: "clinical outcome and exposure history"

Author: Sha Fu; Xiaoyu Fu; Yang Song; Min Li; Pin-hua Pan; Tao Tang; Chunhu Zhang; Tiejian Jiang; Deming Tan; Xuegong Fan; Xinping Sha; Jingdong Ma; Yan Huang; Shaling Li; Yixiang Zheng; Zhaoxin Qian; Zeng Xiong; Lizhi Xiao; Huibao Long; Jianghai Chen; Yi Ouyang
Title: Virologic and clinical characteristics for prognosis of severe COVID-19: a retrospective observational study in Wuhan, China
  • Document date: 2020_4_6
  • ID: 4989atst_5
    Snippet: All of the studied adult patients with COVID-19 infection were hospitalized on February 9, 2020. Forty-eight patients were classified as laboratory-confirmed cases of COVID-19 (diagnosis based on positive viral nucleic-acid test results from throatswab samples), whereas the remaining two patients were clinically diagnosed cases (viral nucleic-acid test was negative, but diagnosis was made based on symptoms, exposure history, and the presence of l.....
    Document: All of the studied adult patients with COVID-19 infection were hospitalized on February 9, 2020. Forty-eight patients were classified as laboratory-confirmed cases of COVID-19 (diagnosis based on positive viral nucleic-acid test results from throatswab samples), whereas the remaining two patients were clinically diagnosed cases (viral nucleic-acid test was negative, but diagnosis was made based on symptoms, exposure history, and the presence of lung-imaging features consistent with coronavirus pneumonia) 11, 12 . Both of the two clinically diagnosed patients were later confirmed using serologic tests for SARS-CoV-2. The medical records from February 9 to March 17, 2020 of the severely ill patients were analyzed. All of the patients were divided into either a good or poor recovery group according to their clinical outcome on March 17, 2020. In addition, the patients were also divided into lung lesions with a partial resolution-patient group and a lung lesions with significant resolution-patient group based on the latest chest CT scans from March 11 to March 17, 2020 . This study was approved by the Ethics Commission of Union Hospital at Tongji Medical College of HUST. Written informed consent was obtained directly from patient. The details of the data sources, procedures for nucleic-acids amplification, serologic tests for SARS-CoV-2, treatments, clinical outcomes, and definitions in this study are provided in the supplementary appendix.

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