Author: Phillip Davis; John Bagnoli; David Yarmosh; Alan Shteyman; Lance Presser; Sharon Altmann; Shelton Bradrick; Joseph A. Russell
Title: Vorpal: A novel RNA virus feature-extraction algorithm demonstrated through interpretable genotype-to-phenotype linear models Document date: 2020_3_2
ID: 48mtdwuv_9
Snippet: with persistent versions of the models described here-in. A simplified example of the 56 agglomerative clustering step is depicted in Figure 1 this motif in the same reading frame but it has returned to the spike protein as QDGVNK. This 130 motif serves as a signal for human pathogenicity whose importance is based at least partially on 131 its translation, though the domain itself can appear in completely different protein products. It 132 was al.....
Document: with persistent versions of the models described here-in. A simplified example of the 56 agglomerative clustering step is depicted in Figure 1 this motif in the same reading frame but it has returned to the spike protein as QDGVNK. This 130 motif serves as a signal for human pathogenicity whose importance is based at least partially on 131 its translation, though the domain itself can appear in completely different protein products. It 132 was also recognized that another positive predictor in the model was a motif related to this one, 133 KGATGTTGTTARWCAAY, offset by a single nucleotide. This related motif sometimes co-134 occurred at the same position as the one mentioned above, and other times appears at a different 135 position in the genome, which suggests this is part of a larger, repetitive motif. 136 This is summarized in
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