Author: Chantal B.F. Vogels; Anderson F. Brito; Anne Louise Wyllie; Joseph R Fauver; Isabel M. Ott; Chaney C. Kalinich; Mary E. Petrone; Marie-Louise Landry; Ellen F. Foxman; Nathan D. Grubaugh
Title: Analytical sensitivity and efficiency comparisons of SARS-COV-2 qRT-PCR assays Document date: 2020_4_1
ID: 6mdimxnk_30
Snippet: Residual de-identified nasopharyngeal samples collected during 2017 (pre-COVID-19) were obtained from the Yale-New Haven Hospital Clinical Virology Laboratory. In accordance with the guidelines of the Yale Human Investigations Committee (HIC), this work with de-identified samples is considered non-human subjects research. These samples were used to create the mock substrate for the SARS-CoV-2 spike-in experiments ( Fig. 3 ) . Clinical samples fro.....
Document: Residual de-identified nasopharyngeal samples collected during 2017 (pre-COVID-19) were obtained from the Yale-New Haven Hospital Clinical Virology Laboratory. In accordance with the guidelines of the Yale Human Investigations Committee (HIC), this work with de-identified samples is considered non-human subjects research. These samples were used to create the mock substrate for the SARS-CoV-2 spike-in experiments ( Fig. 3 ) . Clinical samples from COVID-19 patients during March 2020 at the Yale-New Haven Hospital were collected in accordance to the HIC-approved protocol #2000027690. These samples were used to test the US CDC 2019-nCoV_N1 and 2019-nCoV_N2 primer-probe sets ( Fig. 4 ) .
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