Selected article for: "Ad entry and Ad protein vi"
Author: Wodrich, Harald; Henaff, Daniel; Jammart, Baptist; Segura-Morales, Carolina; Seelmeir, Sigrid; Coux, Olivier; Ruzsics, Zsolt; Wiethoff, Christopher M.; Kremer, Eric J.
Title: A Capsid-Encoded PPxY-Motif Facilitates Adenovirus Entry
  • Document date: 2010_3_19
    • ID: 1mjmttec_25
    Snippet: PPxY motif is essential for protein VI ubiquitylation upon partial Ad disassembly PPxY domains are the physiological targets of ubiquitin ligases of the Nedd4 family [16] . Therefore we asked whether protein VI ubiquitylation depends on the PPxY motif. We adapted an in vitro Ad disassembly assay mimicking the partial capsid disassembly believed to occur during Ad entry by exposing virions to 48uC......
    Document: PPxY motif is essential for protein VI ubiquitylation upon partial Ad disassembly PPxY domains are the physiological targets of ubiquitin ligases of the Nedd4 family [16] . Therefore we asked whether protein VI ubiquitylation depends on the PPxY motif. We adapted an in vitro Ad disassembly assay mimicking the partial capsid disassembly believed to occur during Ad entry by exposing virions to 48uC.

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