Author: Ambrosino, Nicolino; Casaburi, Richard; Chetta, Alfredo; Clini, Enrico; Donner, Claudio F.; Dreher, Michael; Goldstein, Roger; Jubran, Amal; Nici, Linda; Owen, Caroline A.; Rochester, Carolyn; Tobin, Martin J.; Vagheggini, Guido; Vitacca, Michele; ZuWallack, Richard
Title: 8(th) International conference on management and rehabilitation of chronic respiratory failure: the long summaries – Part 3 Document date: 2015_10_6
ID: 08fkra10_65
Snippet: Overall, home NPPV has been shown to improve important physiological parameters in stable hypercapnic COPD patients by the use of a treatment strategy which sufficiently decreases elevated PaCO 2 levels [51] . By doing so, long term survival can be significantly improved. However, the influence of home NPPV to prevent re-hospitalization is still unclear, and future trials are needed to identify the subgroup of COPD patients which benefits most fr.....
Document: Overall, home NPPV has been shown to improve important physiological parameters in stable hypercapnic COPD patients by the use of a treatment strategy which sufficiently decreases elevated PaCO 2 levels [51] . By doing so, long term survival can be significantly improved. However, the influence of home NPPV to prevent re-hospitalization is still unclear, and future trials are needed to identify the subgroup of COPD patients which benefits most from home NPPV. From a clinical point of view, it seems reasonable that patients with acute hypercapnic respiratory failure needing mechanical ventilation in hospital and suffering from prolonged hypercapnia, the ones you can define as acute on chronic hypercapnia respiratory failure, might benefit most. However, inconclusive data are available up to date and further investigation is needed in this area.
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