Author: Ambrosino, Nicolino; Casaburi, Richard; Chetta, Alfredo; Clini, Enrico; Donner, Claudio F.; Dreher, Michael; Goldstein, Roger; Jubran, Amal; Nici, Linda; Owen, Caroline A.; Rochester, Carolyn; Tobin, Martin J.; Vagheggini, Guido; Vitacca, Michele; ZuWallack, Richard
Title: 8(th) International conference on management and rehabilitation of chronic respiratory failure: the long summaries – Part 3 Document date: 2015_10_6
ID: 08fkra10_67
Snippet: There is conflicting evidence regarding the effect of NPPV on reducing health care utilization and mortality in acute on chronic respiratory failure due to COPD. We need to better assess when to initiate this therapy in patients with hypercapnia in this setting. Once stable hypercapnia is proven, NPPV may improve survival and health status. Therefore, despite recent studies adding some new data, the authors cannot recommend the widespread use of .....
Document: There is conflicting evidence regarding the effect of NPPV on reducing health care utilization and mortality in acute on chronic respiratory failure due to COPD. We need to better assess when to initiate this therapy in patients with hypercapnia in this setting. Once stable hypercapnia is proven, NPPV may improve survival and health status. Therefore, despite recent studies adding some new data, the authors cannot recommend the widespread use of this therapeutic intervention after an episode of acute-on-chronic respiratory failure in COPD. There is simply not enough evidence to support it. Instead, this modality should be reserved for individual cases, treated in specialized centers experienced with NPPV for the treatment of stable hypercapnic COPD.
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