Author: Ambrosino, Nicolino; Casaburi, Richard; Chetta, Alfredo; Clini, Enrico; Donner, Claudio F.; Dreher, Michael; Goldstein, Roger; Jubran, Amal; Nici, Linda; Owen, Caroline A.; Rochester, Carolyn; Tobin, Martin J.; Vagheggini, Guido; Vitacca, Michele; ZuWallack, Richard
Title: 8(th) International conference on management and rehabilitation of chronic respiratory failure: the long summaries – Part 3 Document date: 2015_10_6
ID: 08fkra10_11
Snippet: A 45 year-old woman with thoracic restriction developed gradually progressive dyspnea on exertion. Her vital capacity was 43 % predicted, her total lung capacity was 44 % predicted and her forced expired volume in one second to forced vital capacity was 90 %. Arterial blood gases taken on room air showed her to have: pH 7.39, PaCO 2 46 mmHg, PaO 2 78 mmHg, SaO 2 95 %. After an episode of pneumonia a two channel overnight recording showed satisfac.....
Document: A 45 year-old woman with thoracic restriction developed gradually progressive dyspnea on exertion. Her vital capacity was 43 % predicted, her total lung capacity was 44 % predicted and her forced expired volume in one second to forced vital capacity was 90 %. Arterial blood gases taken on room air showed her to have: pH 7.39, PaCO 2 46 mmHg, PaO 2 78 mmHg, SaO 2 95 %. After an episode of pneumonia a two channel overnight recording showed satisfactory oxygenation, mild nocturnal hypercapnia with periodic (likely REM related) worsening of gas exchange (Fig. 2a) . She began to feel unwell over the next few months and on repeat evaluation after 6 months (Fig. 2b) she was noted to have marked hypercapnia. Bi-level positive airway pressure ventilation was initiated electively (Fig. 2c ) and her clinical state as well as her blood gases stabilized. She remains stable on nocturnal non-invasive positive pressure ventilation.
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