Author: Geng, HeYuan; Tan, WenJie
Title: A novel human coronavirus: Middle East respiratory syndrome human coronavirus Document date: 2013_8_7
ID: 08ds967z_1
Snippet: Coronaviruses, a genus in the family Coronaviridae (order Nidovirales), are a large family of viruses that can cause respiratory, enteric, hepatic, nephric and neurological diseases with variable severity in humans and animals. In humans, diseases caused by coronaviruses range from the common cold to severe acute respiratory syndrome (SARS). Based on genome sequence analyses, coronaviruses are phylogenetically divided into three genera known as A.....
Document: Coronaviruses, a genus in the family Coronaviridae (order Nidovirales), are a large family of viruses that can cause respiratory, enteric, hepatic, nephric and neurological diseases with variable severity in humans and animals. In humans, diseases caused by coronaviruses range from the common cold to severe acute respiratory syndrome (SARS). Based on genome sequence analyses, coronaviruses are phylogenetically divided into three genera known as Alph-, Beta-and Gammacoronavirus. Betacoronavirus contains four subgroups, named 2a, 2b, 2c and 2d. A fourth genera, provisionally named Deltacoronavirus, comprises a number of recently identified coronaviruses mainly from birds. Alph-and Betacoronavirus hosts are predominantly domestic mammalian animals and humans, including swine (transmissible gastroenteritis virus, TGEV; porcine epidemic diarrhoea virus, PEDV), bovine (bovine coronavirus, BCoV), mice (mouse hepatitis virus, MHV), dog (canine coronavirus, CCoV), cat (feline infectious peritonitis virus, FIPV) and bat (bat coronavirus HKU4, BatCoV-HKU4). Human coronaviruses (HCoVs) known so far include HCoV-229E, HCoV-OC43, HCoV-HKU1, HCoV-NL63 and SARS (SARS-CoV). Gammacoronavirus comprises primarily avian infectious bronchitis virus (IBV) and beluga whale coronavirus SW1 (BWCoV-SW1) [1]. The emerging of new coronaviruses has been expanding the taxonomic diversity of coronavirus.
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