Selected article for: "CT value and high CT value"
Author: Hercik, Christine; Cosmas, Leonard; Mogeni, Ondari D.; Wamola, Newton; Kohi, Wanze; Houpt, Eric; Liu, Jie; Ochieng, Caroline; Onyango, Clayton; Fields, Barry; Mfinanga, Sayoki; Montgomery, Joel M.
Title: A Combined Syndromic Approach to Examine Viral, Bacterial, and Parasitic Agents among Febrile Patients: A Pilot Study in Kilombero, Tanzania
  • Document date: 2017_12_26
    • ID: 1br7nhzt_30
    Snippet: Our study eligibility criteria and case definitions were not optimized to detect any specific pathogen. We maintained broad and inclusive enrollment criteria given the exploratory nature of our investigation. Of the 56 agents surveyed, Plasmodium was found to be the most common microbe detected, which was consistent with our a priori hypothesis. Given that Kilombero is located in a highly endemic area for malaria, the detection of Plasmodium para.....
    Document: Our study eligibility criteria and case definitions were not optimized to detect any specific pathogen. We maintained broad and inclusive enrollment criteria given the exploratory nature of our investigation. Of the 56 agents surveyed, Plasmodium was found to be the most common microbe detected, which was consistent with our a priori hypothesis. Given that Kilombero is located in a highly endemic area for malaria, the detection of Plasmodium parasitemia in older children and adults is not unexpected and is not necessarily indicative of fever etiology. However, as observed in overall Ct distributions, Plasmodium was detected with the lowest median Ct value (18.5) , signaling relatively high parasite loads among affected individuals. It is also important to recognize that our pilot survey was conducted during the month of June, at the peak season of malaria transmission.

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