Selected article for: "case definition and high specificity"

Author: Shi, Ting; McLean, Kenneth; Campbell, Harry; Nair, Harish
Title: Aetiological role of common respiratory viruses in acute lower respiratory infections in children under five years: A systematic review and meta–analysis
  • Document date: 2015_6_17
  • ID: 13cotyfb_25
    Snippet: Seven of the included studies [17, [20] [21] [22] [23] 25, 36] employed the WHO case definition for pneumonia [43] and this standardised approach enhanced the comparability of results between these studies. These criteria have high sensitivity for pneumonia [44] , but lower specificity with overlap with other conditions [45] , particularly malaria [46] and wheezing disorders. This tends to inflate the number of "cases" and may contribute to an ap.....
    Document: Seven of the included studies [17, [20] [21] [22] [23] 25, 36] employed the WHO case definition for pneumonia [43] and this standardised approach enhanced the comparability of results between these studies. These criteria have high sensitivity for pneumonia [44] , but lower specificity with overlap with other conditions [45] , particularly malaria [46] and wheezing disorders. This tends to inflate the number of "cases" and may contribute to an apparent low level of detection of pathogenic viruses.

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