Author: Lundstrom, Kenneth
Title: Alphavirus-Based Vaccines Document date: 2014_6_16
ID: 07iwwsfz_11
Snippet: Veterinary medicine has also gained from alphavirus vaccine development. In this context, salmonid alphavirus (SAV) replicons were applied for the expression of infectious salmon anemia virus (ISAV) hemagglutinin-esterase (HE) [40] . Intramuscular administration of SAV replicons provided protection against challenges with ISAV in Atlantic salmon. In contrast, intraperitoneal injection was not successful [64] . In another study, DNA vaccines based.....
Document: Veterinary medicine has also gained from alphavirus vaccine development. In this context, salmonid alphavirus (SAV) replicons were applied for the expression of infectious salmon anemia virus (ISAV) hemagglutinin-esterase (HE) [40] . Intramuscular administration of SAV replicons provided protection against challenges with ISAV in Atlantic salmon. In contrast, intraperitoneal injection was not successful [64] . In another study, DNA vaccines based on the SAV E1 and E2 spike proteins were compared to whole virus vaccine in Atlantic salmon [65] . The whole virus vaccine showed superior immunogenicity to the DNA vaccine; the latter provided only marginal reduction in viral replication, and the protection against SAV challenges was no different from controls.
Search related documents:
Co phrase search for related documents- anemia virus and Atlantic salmon: 1, 2, 3, 4
- anemia virus and dna vaccine: 1
- anemia virus and salmon anemia virus: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13
- Atlantic salmon and dna vaccine: 1
- Atlantic salmon and intraperitoneal injection: 1, 2
- Atlantic salmon and salmon anemia virus: 1, 2, 3, 4
- dna vaccine and intramuscular administration: 1, 2, 3, 4, 5, 6, 7, 8, 9
- dna vaccine and intraperitoneal injection: 1, 2
Co phrase search for related documents, hyperlinks ordered by date