Author: Wood, James L. N.; Leach, Melissa; Waldman, Linda; MacGregor, Hayley; Fooks, Anthony R.; Jones, Kate E.; Restif, Olivier; Dechmann, Dina; Hayman, David T. S.; Baker, Kate S.; Peel, Alison J.; Kamins, Alexandra O.; Fahr, Jakob; Ntiamoa-Baidu, Yaa; Suu-Ire, Richard; Breiman, Robert F.; Epstein, Jonathan H.; Field, Hume E.; Cunningham, Andrew A.
Title: A framework for the study of zoonotic disease emergence and its drivers: spillover of bat pathogens as a case study Document date: 2012_10_19
ID: 0pbjttv4_55
Snippet: We describe a framework for the holistic study and management of the emergence of disease from wildlife, focusing on Old World fruit bats as a model. Interdisciplinary approaches are vital, but do not remove the importance of more reductionist studies. The optimal approach will always depend on the precise questions being asked. For example, if the requirement is to undertake a risk assessment of the ability of a range of pathogens in one ecosyst.....
Document: We describe a framework for the holistic study and management of the emergence of disease from wildlife, focusing on Old World fruit bats as a model. Interdisciplinary approaches are vital, but do not remove the importance of more reductionist studies. The optimal approach will always depend on the precise questions being asked. For example, if the requirement is to undertake a risk assessment of the ability of a range of pathogens in one ecosystem to infect humans, then a study focused on understanding host-pathogen interactions, probably initially considering pathogen receptors, would be appropriate. Mechanistic understanding that might be derived from such studies may be important in assessing the ability of particular pathogens to spill over, but does not give insight into the ecology (e.g. types and degrees of exposure) or the rates that the target pathogens are able to cross species barriers.
Search related documents:
Co phrase search for related documents- disease emergence and host pathogen: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
- disease emergence and human infect: 1, 2
- disease emergence and interdisciplinary approach: 1
- disease emergence and mechanistic understanding: 1, 2
- fruit bat and host pathogen: 1
- fruit bat and Old World fruit bat: 1, 2, 3, 4, 5, 6, 7, 8
- fruit bat and Old World fruit bat focus: 1
- fruit bat and optimal approach: 1
- holistic study and management holistic study: 1, 2
- host pathogen and human infect: 1
- host pathogen and interdisciplinary approach: 1
- host pathogen and mechanistic understanding: 1, 2, 3
- host pathogen and optimal approach: 1
- human infect and mechanistic understanding: 1, 2
- interdisciplinary approach and mechanistic understanding: 1
- interdisciplinary approach and optimal approach: 1
Co phrase search for related documents, hyperlinks ordered by date