Selected article for: "central cavity and fusion peptide"
Author: Jones, Harrison G.; Battles, Michael B.; Lin, Chun-Chi; Bianchi, Siro; Corti, Davide; McLellan, Jason S.
Title: Alternative conformations of a major antigenic site on RSV F
  • Document date: 2019_7_15
    • ID: 1r20hl2b_25
    Snippet: Comparison of two prefusion-stabilized RSV F variants, DS (PDB ID: 4MMQ) and Cav1 (PDB ID: 4MMS), highlights the flexibility of site Ø and suggests that a conformational rearrangement of site Ø is required prior to release of the fusion peptide from the central cavity of the trimer during refolding from the prefusion to postfusion state [40] . When only the fusion peptide was anchored by a disulfide bond in the DS structure (PDB ID: 4MMQ), site.....
    Document: Comparison of two prefusion-stabilized RSV F variants, DS (PDB ID: 4MMQ) and Cav1 (PDB ID: 4MMS), highlights the flexibility of site Ø and suggests that a conformational rearrangement of site Ø is required prior to release of the fusion peptide from the central cavity of the trimer during refolding from the prefusion to postfusion state [40] . When only the fusion peptide was anchored by a disulfide bond in the DS structure (PDB ID: 4MMQ), site Ø was acid sequence of residues near RSV F site Ø is shown for both strain A2 and strain B9320. Diamond symbols above each residue indicate a contact between D25 and prefusion RSV F strain A2 based upon PDBePISA analysis of the crystal structure.

    Search related documents:
    Co phrase search for related documents
    • acid sequence and crystal structure pdbepisa analysis: 1, 2
    • acid sequence and fusion peptide: 1, 2, 3, 4, 5, 6, 7, 8, 9
    • acid sequence and pdbepisa analysis: 1, 2
    • central cavity and conformational rearrangement: 1
    • central cavity and crystal structure: 1, 2, 3
    • central cavity and postfusion state: 1
    • conformational rearrangement and crystal structure: 1
    • conformational rearrangement and fusion peptide: 1, 2, 3
    • conformational rearrangement and postfusion state: 1
    • crystal structure and disulfide bond: 1, 2, 3, 4, 5, 6, 7, 8
    • crystal structure and fusion peptide: 1, 2, 3, 4, 5, 6, 7
    • crystal structure and near residue: 1
    • crystal structure and pdbepisa analysis: 1, 2
    • crystal structure and postfusion state: 1, 2
    • crystal structure pdbepisa analysis and pdbepisa analysis: 1, 2
    • disulfide bond and fusion peptide: 1, 2
    • DS structure and fusion peptide: 1
    • fusion peptide and postfusion state: 1, 2, 3, 4, 5, 6